Apr 13-14, 2016 • Boston, MA
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Sustained Release/Drug Attachment Technology
Sustained drug attachment and release therapies provide a framework to release therapeutic agents over an extended time period from a medical device.
One-step application of complex
#1 is a surface, #2 is an optional hydrophillic polymer, #3 are clevable linkages, #4 is an anchor provided by reactive polymer chains in the complex and #5 is an embedded and exposed bioactive material.
Two-step application of a complex
#1 is a surface, #2 is a layer of a reactive anchor containing linker moiety or a linker moiety alone over reactive surface, #3 is a cleavable linkage and #4 is a bioactive material.
- Therapeutic agents are released locally from devices to provide maximum benefit where the treatment is most needed.
- Release rate and time period are customized to optimize the clinical benefit.
- Optimized, site-specific dosages are administered without adverse effects common to systemic treatments.
Off the shelf:
- Antiangiogenesis factors
Your protein/gene therapy for:
- Cell growth regulation
- Immune response regulation
- Skin/organ tissue
- Cancer treatments
- Neural/ocular system
Let your imagination find the limits